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KMID : 1161420220250020213
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Journal of Medicinal Food
2022 Volume.25 No. 2 p.213 ~ p.218
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A Quadruple Coating of Probiotics for Enhancing Intestinal Adhesion and Competitive Exclusion of Salmonella Typhimurium
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Bang Won-Yeong
Kim Ha-Young
Chae Seung-A
Yang Soo-Yeon
Ban O-Hyun
Kim Tae-Yoon
Kwon Hyuk-Sang
Jung Young-Hoon
Yang Jung-Woo
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Abstract
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Previously, our group showed that a quadruple coating of probiotics resulted in higher survivability of probiotics under high acid, bile salt, and thermal stresses. In this study, we evaluated the effect of the quadruple coating of probiotics on adhesive properties as well as on competitive exclusion of Salmonella Typhimurium in Caco-2 cells. We found that the quadruple coating of probiotics exhibited an overall increased adhesion property (up to 10.8-fold) and increased competitive exclusion of Salmonella Typhimurium (up to 4.3-fold). Thus, this study has significant implications and can lead to the development of methods that can improve the adhesive ability of probiotics as well as the adhesive inhibition of pathogens.
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KEYWORD
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adhesion, microencapsulation, probiotics, quadruple coating, Salmonella Typhimurium
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